PUBLICATIONS

1. Biochemical Markers of the Alzheimer Disease

1. Bartoš A, Fialová L, Švarcová J, Řípová D. Patients with Alzheimer disease have elevated intrathecal synthesis of antibodies against tau protein and heavy neurofilament. Journal of Neuroimmunology, 2012; 252(1-2): 100–105. [LINK Abstract] 
2. Petzold A, Altintas A, Andreoni L, Bartos A et al. Neurofilament ELISA validation. J Immunol Methods 2010, 352(1–2): 23–31 [LINK Abstract]
3. Hort J, Bartos A, Pirttilä T, Scheltens P. Use of cerebrospinal fluid biomarkers in diagnosis of dementia across Europe. Eur J Neurol 2010; 17(1): 90–96 [LINK Abstract]
4. Kristofikova Z, Bockova M, Hegnerova K, Bartos A, Klaschka J, Ricny J, Ripova D, Homola J. Enhanced levels of mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 in patients with Alzheimer disease and multiple sclerosis. Mol Biosyst. 2009:1174–9 [LINK Abstract]
5. Fialová L, Bartoš A, Soukupová J, Švarcová J, Ridzoň P, Malbohan I. Synergy of serum and cerebrospinal fluid antibodies against axonal cytoskeletal proteins in patients with different neurological diseases. Folia Biol 2009; 55: 23–26 [LINK Abstract]
   Hegnerová K, Bocková H, Vaisocherová H, Krištofiková Z, Říčný J, Řípová D, Homola J. Surface plasmon resonance biosensors for detection of Alzheimer disease biomarker. Sensor Actuat. B-Chem. 139 (2009), 69–73.
   

Published 2005 and before

1. Řípová D, Platilová V, Strunecká A, Jirák R and Höschl C: Cytosolic calcium alterations in platelets of patients with early stages of Alzheimer’s disease. Neurobiolog. Aging 21/5, 2000, 729–734.
2. Řípová D, Strunecká A. An ideal biological marker of Alzheimer’s disease: dream or reality? Physiol. Res. 50, 2001, 119–129.
3. Řípová D, Platilová V, Jirák R. Calcium dyshomeostasis in the course of disease in individual patients with Alzheimer dementia. In: New Trends in Alzheimer and Parkinson Related Disorders (I.Hanin, A.Fisher and R.Cacabelos, eds). Medimond, Bologna, 2003, p. 53–56.
4. Řípová D, Platilová V, Strunecká A, Jirák R, Höschl C. Alterations in calcium homeostasis as biological marker for mild Alzheimer’s disease? Physiol.Res. 53/4, 2004, 449–452.
5. Bičíková M, Řípová D, Hill M, Jirák R, Havlíková H, Tallová J, Hampl R. Plasma levels of 7-hydroxylated DHEA metabolites and selected aminothiols as discriminatory tools of Alzheimer´s disease and vascular dementia. Clin. Chem. Lab. Med. 42/5, 2004, 518–524.
   

2. Changes of the Brain caused by the Normal Aging or AD

1. Krištofiková Z, Řípová D, Bartoš A, Bocková M, Hegnerová K, Říčný J, Čechová L, Vrajová M, Homola J. Neuroinflammation and complexes of 17beta-hydroxysteroid dehydrogenase type 10 - amyloid beta in Alzheimer’s Disease. Current Alzheimer Research, 2013; 10(2): 165-173. [LINK FullText]
2. Říčný J. Overlooked Alzheimer's Smoking Gun? Neurochemical Research, 2013; 38(9): 1774-1776. [LINK FullText]
3. Garcia-Sierra F, Basulto JJJ, Krištofiková Z, Majer E, Binder LI, Řípová D. Ubiquitin is associated with early truncation of tau protein at aspartic acid421 during the maturation of neurofibrillary tangles in Alzheimer’s disease. Brain Pathology, 2012; 22(2): 240-250. [LINK FullText]
4. Kolářová M, Garcia-Sierra F, Bartoš A, Říčný J, Řípová D. Structure and pathology of tau protein in Alzheimer disease. International Journal of Alzheimer’s Disease, 2012; 2012(Article ID 731526, Online 29 May 2012): 1-13. [LINK FullText]
5. Krištofiková Z, Kozmiková I, Hovorková P, Říčný J, Zach P, Majer E, Klaschka J, Řípová D. Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia. Neurochem Int. 53, 2008, 118–125.
6. Hovorková P, Krištofiková Z, Hořínek A, Řípová D, Majer E, Zach P, Sellinger P, Říčný J. Lateralization of 17beta-hydroxysteroid dehydrogenase type 10 in hippocampi of demented and psychotic peoples. Dement. Geriatr. Cogn. Disord. 26, 2008, 193–198.
7. Zach P, Krištofiková Z, Mrzílková J, Majer E, Sellinger P, Španiel F, Řípová D, Kenney J. Planum temporale analysis via a new volumetric method in autoptic brains of demented and psychotic patients. Curr. Alzh. Res. 6, 2009, 69–76.
   

Published 2005 and before

1. Tuček S, Doležal V, Říčný J. Factors affecting the synthesis of acetylcholine in the brain. In: Alzheimer's Disease: Advances in Basic Research and Therapies (RJ Wurtman, SH Corkin and JH Crowdon, eds), Cambridge, MA, 1984, p.113–122.
2. Tuček S, Říčný J, Doležal V. Advances in the biology of cholinergic neurons. In: Advances in Neurology, vol. 51: Alzheimer's Disease (R.J. Wurtman, S.Corkin, J.H. Crowdon and E.Ritter-Walker, eds), Raven Press, New York, 1990, pp. 109–115.
3. Tuček S, Říčný J, Doležal V. Advances in cholinergic research relevant to problems of aging. In: Aging and Dementia: New Trends in Diagnosis and Therapy (L.Battistin and F.Gerstenbrand, eds), Alan R. Liss, New York, 1990, p. 203–214.
4. Krištofiková Z, Klaschka J, Němcová V, Majer E, Fales E. Effect of postmortem storage on the (3H)hemicholinium-3 binding site in the rat brain. Preliminary study for investigations of human patients with Alzheimer´s disease. Arch. Gerontol. Geriatr. 16, 1993, 117–128.
5. Krištofiková Z, Benešová O, Tejkalová H. Comparison of the effects of aging in vivo and of oxygen free radicals in vitro on high-affinity choline uptake and hemicholinium-3 binding in the rat brain. Arch. Gerontol. Geriatr. 19, 1993, 179–188.
6. Krištofiková Z, Fales E, Majer E, Klaschka J. (3H)Hemicholinium-3 binding sites in postmortem brains of human patients with Alzheimer’s disease and multi-infarct dementia. Exp. Gerontol. 30/2, 1995, 125–136.
7. Krištofiková Z, Klaschka J, Tejkalová H. Effect of aging on lipid peroxide levels induced by L-glutamic acid and estimated by means of a thiobarbituric acid test in rat brain tissue. Exp. Gerontol. 30/6, 1995, 645–657.
8. Krištofiková Z, Majer E, Fales E, Pěkný I, Klaschka J. Effects of aging and dementia on the levels of thiobarbituric-acid reactive products stimulated by L-glutamic acid in human autopsy and biopsy tissue. Dement. Geriatr. Cogn. Disord. 9, 1998, 6–12.
9. Řípová D, Němcová V, Höschl C, Fales E, Majer E, Strunecká A. Lipid composition of different brain regions in patients with Alzheimer’s disease and multi-infarct dementia. In: Progress in Alzheimers, Parkinson’s diseases (A.Fisher, M. Yoshida, I.Hanin, eds). Medimond, Bologna, 1998, p. 301–308.
10. Krištofiková Z, Klaschka J, Tejkalová H. Effects of K+-depolarization, arachidonic acid, ethanol, and aging on the high-affinity choline transport in rat hippocampus. Neurochem. Res. 23/7, 1998, 923–929.
11. Zach P, Krištofiková Z, Majer E, Selinger P, Řípová D. Alterations in the planum temporale in patients with Alzheimer disease estimated via a new volumetric method. In: New Trends in Alzheimer and Parkinson Related Disorders (A.Fisher, I.Hanin, M.Memo and F.Stocchi, eds). Medimond, Bologna, 2005, p. 171–176.

3. Animal Models of AD

Published 2005 and before

1. Krištofiková Z, Šťastný F, Bubeníková V, Druga R, Klaschka J, Španiel F. Age- and sex-dependent laterality of rat hippocampal cholinergic system in relation to animal models of neurodevelopmental and neurodegenerative disorders. Neurochem. Res. 29/4, 2004, 671–680.

4. Medication of the Cognitive Functions of the Brain

Published 2005 and Before

1. Benešová O, Krejčí I, Pavlík A. Nootropic Drugs. Avicenum, Prague, 1991.
2. Krištofiková Z, Benešová O, Tejkalová H. Changes of high-affinity choline uptake in the hippocampus of old rats after long-term administration of two nootropic drugs (tacrine and Ginkgo biloba Extract). Dementia 3, 1992, 304–307.
3. Krištofiková Z, Klaschka J. In vitro effect of Ginkgo biloba Extract (EGb 761) on the activity of presynaptic cholinergic nerve terminals in rat hippocampus. Dement. Geriatr. Cogn. Disord. 8, 1997, 43–48.

5. Peptides of the Beta-Amyloide and Tau in an Experiment in vitro

1. Krištofiková Z, Řípová D, Hegnerová K, Šírová J, Homola J. Protein tau-mediated effects on rat hippocampal choline transporters CHT1 and tau-amyloid beta interactions. Neurochemical Research, 2013; 38(9): 1949-1959.  [LINK FullText]
2. Kříž Z, Klusák J, Krištofiková Z, Koča J. How ionic strength affects the conformational behavior of human and rat beta amyloids – a computational study. PLoS One, 2013; 8(5): "e62914".  [LINK FullText]  
3. Krištofiková Z, Kříž Z, Řípová D, Koča J. Interactions of amyloid beta peptide 1-40 and cerebrosterol. Neurochemical Research, 2012; 37(3: 604-613.  [LINK FullText] 
4. Krištofiková Z, Říčný J, Kozmiková I, Řípová D, Zach P, Klaschka J. Sex-dependent actions of amyloid beta peptides on hippocampal choline carriers of postnatal rats. Neurochem. Res. 31, 2006, 351–360.
5. Krištofiková Z, Kopecký V, Hofbauerová K, Hovorková P, Řípová D. Complex of amyloid beta peptides with 24-hydroxycholesterol and its effect on hemicholinium-3 sensitive carriers. Neurochem. Res. 33 (2008), 412–421.

Published 2005 and before

1. Krištofiková Z, Tejkalová H, Klaschka J. Amyloid beta peptide 1-40 and the function of rat hippocampal hemicholinium-3 sensitive choline carriers: effects of a proteolytic degradation in vitro. Neurochem. Res. 26/3, 2001, 203–212.

6. Functional and Structural Imaging of Brain in the Patients with Alzheimer Disease

1. Mrzílková J, Zach P, Bartoš A, Tintěra J, Řípová D. Volumetric analysis of the pons, cerebellum and hippocampi in patients with Alzheimer’s disease. Dementia and Geriatric Cognitive Disorders, 2012; 34(3-4): 224-234. [LINK FullText]
2. Ibrahim I, Horacek J, Bartos A, Hajek M, Ripova D, Brunovsky M, Tintera J. Combination of Voxel Based Morphometry and Diffusion Tensor Imaging in Patients with Alzheimer’s Disease. Neuroendocrinology Letters, 2009;30(1):101–107 [LINK Abstract]
3. Kukal J, Bartoš A, Řípová D. Radial approach to 3D magnetic resonance morphology of brain in Alzheimer disease classification. Psychiatrie 2006; 10 (Suppl. 3): 43–44 [LINK FullText]

7. Neuropsychological and Psychometrical Research and Diagnostics in Patients with Cognitive Disorders

1. Štěpánková H, Jarolímová E, Dragomirecká E, Sobotková I, Šulová L, Bezdíček O, Nikolai T, Pulkrabková A, Bergerová M, Vácha T, Kolda P, Holmerová I. On geropsychology in the Czech Republic. GeroPsych, 2012; 25(3): 161–166.
2. Štěpánková H, Lukavský J, Kopeček M, Steinová D, Řípová D. Modification of subjective cognitive outcomes in older persons through memory training. GeroPsych, 2012; 25(3): 117–125.